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If you are eating a low-fiber, highly processed diet, the probiotic bacteria do not have the substrate they need to produce meaningful amounts of butyrate and P9

Neuropsychopharmacology 39 (13), 30093017

It works like a GLP-1 agonist, but also targets a hormone called glucose-dependent insulinotropic polypeptide (GIP) to help break down sugar and fat, according to Chatham

RetatrutideA Game Changer in Obesity Pharmacotherapy

6 Healthy dWAT secretes anti-inflammatory adipokines, such as leptin and adiponectin, that stimulate fibroblasts to synthesize collagen, elastin, and hyaluronic acid