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Co-crystal structures of GSTO1 bound to inhibitors showed a covalent association with the active site cysteine (C32) with additional hydrophilic and hydrophobic interactions in the H-site

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At that time, physicians were often reluctant to diagnose this multifaceted clinical syndrome as long COVID because routine diagnostics of blood samples or imaging in survivors of mild acute COVID-19 rarely yielded any pathological results [120]