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E.et al (2025)

As with all GLP-1 receptor agonists, there are class-level safety considerations to be aware of, based on UK Summary of Product Characteristics (SmPC) for approved agents such as semaglutide (Wegovy): Pancreatitis : If pancreatitis is suspected indicated by severe, persistent abdominal pain, which may radiate to the back treatment should be stopped immediately and urgent medical assessment sought

All findings referenced are from preclinical research and early-phase investigations

The compound activates the GIP receptor (glucose-dependent insulinotropic polypeptide), the GLP-1 receptor (glucagon-like peptide-1), and the glucagon receptor simultaneously [1]

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