This project has received funding from the European Research Council under the European Unions Horizon 2020 research and innovation programme (COBREX
Vegans or vegetarians are more likely to have a B12 deficiency
This NAD+ elevation activates sirtuins, particularly SIRT1 in adipocytes and hepatocytes, which deacetylates and activates numerous metabolic regulatory proteins including PGC-1, a master regulator of mitochondrial biogenesis, oxidative metabolism, and thermogenesis
Selank is an anxiolytic-researched neuropeptide associated in the literature with the modulation of anxiety, stress reactivity, and GABAergic signaling
Overall, this comprehensive experimental design allowed for the evaluation of Epitalons effects on key aspects of oocyte physiology, including oxidative stress response, mitochondrial function, spindle morphology, and developmental potential