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Integration of O-GlcNAc into stress response pathways

Importantly, the context-dependent effects of metformin, including its reduced benefit in APOE-4 carriers and potential risks in non-DM2 populations, emphasize the need for stratified patient selection when considering DM2 DMTs for AD prevention

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In conclusion, while carnitine plays a vital role in energy production and may have potential benefits for certain neuropsychiatric conditions, its use should be approached with caution