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Bibcode:2010Sci...328..636R

Clinical labs were measured at the NIH Clinical Laboratory and, for MGH, at LabCorp and Quest

This mechanism becomes clinically important when using high-dose oral supplements (typically 1000 micrograms or more), as it can provide adequate absorption even when the intrinsic factor pathway is impaired

Four metabolites involved in CBS-catalyzed reactions, Hcy, serine, Ctt, and H 2 S, are bioactive metabolites involved in diverse biological functions including mitochondrial bioenergetics, redox homeostasis, DNA methylation, and protein modification 62

doi: 10.1021/acs.jafc.0c05834 41 WangGPanRLiangXiWuXWuYZhangHet al