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Long chain fatty acids and dietary fats in fetal nutrition

doi: 10.1089/thy.2018.0116 145 OrlovSSalariFKashatLWalfishPG

10.1016/j.abb.2019.108241 12

Immune-cell activation can reorganize nutrient use, NADPH production, mitochondrial metabolism, and thiol-dependent signaling, making glutathione regulation one component of broader immunometabolic control

Thus, it is critical to elucidate if the accumulation of autophagosomes upon LDHB silencing is due to an increased frequency of damaged mitochondria, a deficiency in lysosome-dependent mitophagy, or a combination thereof