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In the lymph nodes, there was a significant decrease in immune gene transcription and a marked upregulation of the renin-angiotensin-aldosterone system (RAAS) pathway, which coincided with histological scarring

A 100mg vial reconstituted with 5mL produces 20mg/mL, while a 50mg vial with the same 5mL produces 10mg/mL meaning the same target dose corresponds to twice the volume in the smaller vial

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