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Increased plasma medium and long chain acylcarnitines (Figure 5, Group 2) can otherwise result from different processes such as increased physical activity or extended fasting in which the efflux of acylcarnitines exceeds the capacity for complete oxidation of the fatty acids (65, 66)

Both are used for diabetes management

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Constitutive MAPK phosphorylation and pharmacodynamic inhibitio of MEK/MAPK in relapsed/refractory primary acute myelogenous leukemia (AML) cells

(Teixeira et al., 2005)