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Short bouts of exercise, regardless of intensity, tend to induce little or no change in RBC deformability, while prolonged endurance activity can lead to more pronounced alterations (Koliamitra et al., 2017

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pmc.ncbi.nlm.nih.gov/articles/PMC4508379 Abdulghani AA, Sherr S, Shirin S, et al

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2.2 Nano-bio interface parameters and in vivo behavior Translating these objectives into concrete nanocarrier architectures first requires specifying a set of nano-bio interface parameters that govern in vivo behavior [33, 37]