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J., & Greenway, F

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Regulating Blood Sugar: Balanced blood sugar levels help prevent insulin spikes, which can lead to fat storage, especially around the midsection

In 2012, our group reported a novel (4 + 3) strategy for preparing cyclohepta[ b ]indoles in a single chemical transformation by means of a three-component annulation reaction beginning with an indole, a carbonyl, and a diene 2

Recognition of this has spurred a number of innovative approaches that, despite their preclinical promise, have yielded disappointing efforts at translation into a meaningful clinical role