Stevens JE, Horowitz M, Deacon CF, Nauck M, Rayner CK, Jones KL
For individuals with arthritis, achieving and maintaining weight loss can be challenging due to: Pain-related activity limitation , making exercise difficult Reduced mobility affecting ability to engage in physical activity Medication side effects , as some arthritis treatments may affect metabolism Nevertheless, structured weight management programmes combining dietary modification, physical activity tailored to individual capabilities, and behavioural support have proven effective
Nevertheless, failures to achieve maximal weight loss and maintain the weight loss achievement have been described
they serve different patient populations and have distinct supply chains
DS develops various complications such as neurological, skeletal, cardiovascular, and immunological defects 1 , but is perhaps best known for being the most common genetic cause of mental retardation and intellectual disability 2 , occurring at a rate of 1 in 800 to 1000 births 3,4
