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It's possible that AOD9604 may influence the fat cells and lipolytic receptors, particularly given its observed association with changes in weight and fat in murine models

Because it competes at the nicotinamide substrate site rather than the SAM cofactor site, it is also used as the substrate-competitive reference compound against which bisubstrate and covalent NNMT inhibitors are benchmarked

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They proposed that NNMT may lead to obesity

They are not intended to represent clinical evidence in humans, and 5-Amino-1MQ has not been approved by the FDA, EMA, or any other regulatory authority for any indication