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In contrast, non-responders more frequently display dysbiotic profiles enriched in taxa linked to insulin resistance and inflammatory metabolism, such as P

They have emerged as key therapeutic targets in diabetes and obesity research , inspiring the development of dual and triple receptor agonists that synergistically enhance glycemic control, promote weight loss, and improve overall metabolic health

Obesity has become a major global health crisis impacting every corner of the world, with some of the most rapid increases in prevalence seen in low- and middle-income countries

Autophagy deficiency exacerbates iron overload induced reactive oxygen species production and apoptotic cell death in skeletal muscle cells [J]