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All cell types, including lymphocytes and other immune cells, have a complex machinery of antioxidant enzymes (superoxide dismutase, catalase, glutathione peroxidase, glutathione reductase, thioredoxin etc.) and antioxidant molecule (reduced glutathione, vitamins) for regulating oxidant reactions in the cells prevent free radical mediated cytotoxicity [54]

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It introduces more variables and makes it impossible to gather consistent data

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Therapeutically, small trials in humans are underway: one randomized trial in mild AD is testing an oral broad-spectrum antibiotic followed by FMT to reset the microbiome [142]