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Vero treated with erastin significantly regulated the expression of three genes, NRF2 , ACSL4 and GPX4 , notably erastin regulated the expression of these three genes negatively correlated with the expression induced by PEDV virus infection

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Female gender, high pre-prophylaxis attack frequency, predominant abdominal attacks and Berotralstat treatment were associated with resistance to prophylaxis

How It Is Studied Glutathione levels in research samples are typically quantified using the DTNB (Ellman's reagent) colorimetric assay, HPLC with electrochemical or fluorescence detection, or mass spectrometry-based metabolomic panels