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Dermal and Collagen Studies Laboratories frequently examine GHK-Cu for its potential role in fibroblast proliferation and collagen deposition, which may illuminate processes behind scar reduction and wound closure [2]

Fe 3+ can act as a catalase-like nanozyme to transform H 2 O 2 into O 2 , relieving the hypoxic condition in TME and boosting oxygen-based PDT and SDT

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However, these comparisons are primarily derived from indirect cross-trial analyses rather than head-to-head randomized trials, thereby limiting the strength of evidence