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Although the two agents have different mechanisms tirzepatide acts on both GIP and GLP-1 receptors, whilst semaglutide acts on GLP-1 receptors alone understanding the proposed mechanisms is relevant to both, with the important caveat that evidence for a direct drug class effect on hair follicles is currently lacking

For more information about this advisory, kindly contact the FDA Center for Food Regulation and Research via e-mail at [email protected],

Outgoing FDA Commissioner Robert Califf and other experts have raised concerns about the safety of compounded drugs sold online, emphasizing that patients may not fully understand what they are purchasing