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In contrast, SIRT3 and SIRT5 improve mitochondrial function, as manifested by reduced ROS production during oxidative phosphorylation (136)

Oxidative stress occurs when the body has too many unstable molecules called pro-oxidants free radicals and reactive oxygen species (ROS)

treated THP-induced macrophages co-cultured with human bronchial epithelial cells with cigarette smoke extract, observing elevated levels of nuclear receptor coactivator 4 (NCOA4)

Nicholas Perricone, world-renowned author of New York Times bestseller, The Wrinkle Cure

The two therapies work in tandem: one purifies at the cellular level, the other clears the pathways that carry waste away