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GSTP1 itself can also function as a target, as has been shown for chemically reactive metabolites derived from acetaminophen (Jenkins et al., 2008) and diclofenac ( Although reactive QI formation has been associated with AQ-induced (cyto)toxicity in vitro (Naisbitt et al., 1998

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UPLCQQQ-MS Analysis: Samples were analyzed using Agilent 1290 UPLC coupled with Agilent 6495B triple quadrupole mass spectrometry, operated in MRM mode for maximum specificity and sensitivity