Mol Cell Biol 28:133847, PMID: 18086890 Haddad JJ (2002) The involvement of l-gamma-glutamyl-l-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production
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According to the TCGA database, The expression levels of SLC7A11 mRNA in Cervical cancer (CESC), Cholangiocarcinoma (CHOL), Colonic adenocarcinoma (COAD), Esophagus cancer (ESCA), Head and neck squamous cell carcinoma (HNSC), chromophobe kidney cell carcinoma (KICH), Clear cell carcinoma of kidney (KIRC), Papillary cell carcinoma of the kidney (KIRP), Liver cell carcinoma (LIHC), Lung adenocarcinoma (LUAD), Squamous cell carcinoma of the lung (LUSC), Adenocarcinoma of the pancreas (PAAD), Rectum adenocarcinoma (READ), Sarcoma (SARC), Cutaneous melanoma (SKCM), Stomach adenocarcinoma (STAD), and Endometrial carcinoma of the flesh (UCEC) were significantly higher than those in adjacent normal tissues
A low ratio might suggest that your body is using up its antioxidant stores faster than it can replenish them
F.ZhangS.ZhaoF.LiY.et al (2008b)