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First, acute and chronic EtOH administration induce overproduction of ROS, RNS and other free radicals, observations made in cell cultures, experimental animals and human subjects

10.1016/j.jad.2020.05.026 5 ChenY.LiS.ZhaoJ.CaoX.WangF

examined the expression of CPT-1 isoforms in photoreceptor cells and retinal pigment epithelial cells that are known to be affected morphologically and functionally in complete MTP deficiency and deficiency of long-chain 3-hydroxyacyl-CoA hydratase (LCHAD) [167]

US Army Electronic Proving Ground, Fort Huachuca, AZ

In the context of NAFLD, excess glucose is metabolized to acetyl-CoA via glycolysis, contributing to lipogenesis