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Therapeutic Potential MOTS-c is naturally present in human blood and tissues, and the effects of disease and exercise on endogenous levels have been investigated in human studies

Yu, H.-J

The acetyl form supports both the metabolic side (shuttling long-chain fatty acids into the mitochondria for energy production, which is the mechanism behind L-Carnitine's documented fat-mobilisation effects) and the cognitive side (mental energy, mood support, alertness, and reduced mental fatigue)

CTS is most common in females aged between 40-60 years old and individuals with diabetes mellitus other risk factors for are: Overloading the wrist and/or fingers Previous wrist fracture or injury Pregnancy Arthritis CTS is characterised by gradual onset of pain into the palm side of the wrist and numbness or paraesthesia (tingling or pins and needles) into the thumb, index finger, middle finger and the inner half of the ring finger (pictured below)

Data sources for all outcomes have listed in Additional file 1: Table S1