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Any psoriasis improvement with GLP-1 therapy likely occurs indirectly through substantial weight loss, which reduces systemic inflammation and pro-inflammatory adipokines

In terms of CR, one study showed men who had accelerated bone loss were associated with a lower trabecular bone volume fraction (BV/TV), lower cortical thickness, and higher trabecular separation [32]

All research must be conducted by qualified professionals in properly equipped laboratory environments and in compliance with applicable regulations and safety standards

8.5 Kidney Function Impairment Due to Dehydration Severe gastrointestinal symptoms may lead to dehydration, adversely affecting renal function