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2.2 Dextran sulfate sodium (DSS)-Induced colitis and treatments The animal experiments were carried out in compliance with the ARRIVE guidelines 2.0 to assure the adequate management of animals ( 2.3 Histological analysis Paraffin-embedded blocks were prepared following the standard dehydration and 24-h fixation of excised colonic specimens in 10% neutral buffered formalin

A statistically significant increase in the frequency of pre- implantation losses in mice (Q strain) in the second week and fifth week of mating has been observed after a single intraperitoneal injection of 10 mg/kg body weight (Degraeve et al., 1980

R., Warner, A

Signs of degradation Degraded GHK-CU may show visible changes: Cloudiness or particles in the solution Color changes (fresh solution should be clear to slightly yellowish) Unusual smell Clumping or precipitation When in doubt, discard

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