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Studies use the CJC-1295 Without DAC + Ipamorelin combination to examine the mechanistic basis of GHRH/GHRP synergy characterising cAMP/calcium signal integration, the role of GHS-R1a in amplifying GHRH-driven cAMP responses, and the pituitary intracellular signalling nodes at which the two pathways converge to produce amplified GH secretory responses

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