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Se, being a cofactor of GPX which protects body cells from damage by free radicals, is essential for reduction of inflammation and maintenance of the integrity of cell function, while Se deficiency predisposes to inflammation and diminishes the inflammatory response: supplementation effectively attenuates inflammatory activity [40]

This decline may be closely associated with energy metabolism disorders, oxidative stress-induced cellular damage, and disrupted membrane function in sperm cells [9, 36,37,38]

Food sources include nuts, seeds, and vegetable oils