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TB-500 may therefore be hypothesized to encourage angiogenesis by pairing a cytoskeleton-linked rise in endothelial motility with signaling shifts that elevate pro-angiogenic programs such as VEGF-A and Ang2/Tie2 through Notch/NF-B coupling in damaged cellular structures

Introduce compressed air at a pressure of 0.10.15 MPa, maintaining an air-scouring flow rate of 23 m/(mmin), and continue mixing for 35 minutes

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