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doi: 10.3389/fnins.2018.00930 87 VaratharajA.GaleaI

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This hormone helps regulate blood sugar by stimulating insulin secretion and also signals the brain to promote feelings of fullness.[121] When administered, GLP-1 therapies mimic the bodys natural post-meal responseeven in the absence of foodresulting in prolonged satiety, delayed digestion, and sustained insulin release

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The speed of tirzepatide onset after restarting depends on how long the gap was and what dose you left off at