Biomolecules 11(4):612 Codolo G, Plotegher N, Pozzobon T, Brucale M, Tessari I, Bubacco L et al (2013) Triggering of inflammasome by aggregated alpha-synuclein, an inflammatory response in synucleinopathies
Through multi-target mechanisms, these active metabolites either directly activate the -catalytic subunit of AMPK (via phosphorylation at Thr172) or indirectly modulate upstream kinases (such as LKB1 and CaMKK ), thereby influencing the expression and activity of downstream key effector molecules, including ACC, SREBP-1c, and PPAR
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doi: 10.1016/j.pnpbp.2010.08.010
Nitric Oxide Pathway: It seems to influence the nitric oxide pathway, which plays a role in vasodilation and reducing inflammation