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In addition to morphological examinations of lymphoid organs, a selection of non-lymphoid tissues (e.g., blood vessels, renal glomeruli, synovial membranes, thyroid, skin, liver and lungs) should be investigated

If symptoms cannot be adequately distinguished from Crohn's activity, temporary discontinuation may be necessary to clarify the clinical picture

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Both Zepbound (tirzepatide) and Wegovy (semaglutide GLP-1) typically begin to show noticeable effects on appetite and weight within the first month of treatment