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PMID: 12877710

This accumulation likely further contributes to blood vasculature dysfunction, as it has been shown that chronically elevated sodium levels can lead to endothelial glycocalyx dysfunction and inflammation (Schierke et al., 2017)

Nevertheless, further studies are required to elucidate the exact role and underlying molecular mechanisms of the trans-sulphuration pathway in cancer cell death

A study reported that retinoid acid can cause significant trans-epidermal water loss (TEWLs) that can further impair skin barrier and induce more skin irritation [3]