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The Y-located proto-oncogene TSPY exacerbates and its X-homologue TSPX inhibits transactivation functions of androgen receptor and its constitutively active variants

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In contrast, patients with Graves disease, an autoimmune disease that generates anti-TSH autoantibodies and causes hyperthyroidism, are highly susceptible to seasonal allergic diseases (42.9% in patients with Graves disease