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GLP-1 secretion is primarily triggered by the presence of nutrientsparticularly carbohydrates, fats, and proteinsin the intestinal lumen

This strain will be available at The Jackson Laboratory Repository with the JAX 040551 Glp1r S33W mouse line

doi: 10.1016/0020-7292(91)90645-l 39 LundmanBAsplundKNorbergA

Cardiovascular disease risk factor responses to a type 2 diabetes care model including nutritional ketosis induced by sustained carbohydrate restriction at 1 year: an open label, non-randomized, controlled study

NNT activity contributes to 45% of the total NADPH in mitochondrial pool, indicating a significant role of NNT for NADPH pool maintenance, 111 and NADPH obtained by NNT is also used for the reductive carboxylation of -KG to isocitrate mediated by IDH2