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Background Proximal tubule cells are used as an in vitro model for studies on nephrotoxicity and the method developed by Boogaard et al [1,2] yields 90-95% of proximal tubule cells with a high viability (97%)

The AMBER ff14SB force field, General AMBER force field (GAFF) 68 , and TIP3P 69 water model were employed for the protein, including bivalent and monovalent ions, 25HC, and solvent molecules, respectively

In reaction to AD, astrocytes experience a shift in profile, one that is reactive and pro-inflammatory while losing homeostatic roles thus disrupting BBB integrity, ion and neurotransmitter buffering, and energy metabolism (Liddelow et al., 2017

Vegetarians and Vegans Vegetarians and vegans are more likely to experience a B12 shortage because animal products provide the majority of this vitamin

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