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They found that, although immunoreactive glucose-dependent insulinotropic polypeptide (GIP) responses to an oral glucose load were not different between controls and diabetic patients, there was an impaired incretin effect in the face of normal GIP levels in patients with type 2 diabetes

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Role of matrix metalloproteinases in epithelial migration

The addition of DPP-4 inhibitors to patients already treated with metformin may seem particularly attractive, since both drugs may act to enhance circulating levels of GLP-1 and thus, may have synergistic effects on incretin receptor signaling [44,45,46]

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