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This hormone is believed to be transmitted by sensory neuron cells in the gut and is rapidly metabolized there by an enzyme called dipeptidyl peptidase

These two modalities can be effective once laxity develops

doi: 10.1016/S0140-6736(15)00803-X 193 NewsomePNBuchholtzKCusiKLinderMOkanoueTRatziuVet al

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Amylin therapies Some drugs currently in development take a different approach, targeting receptors for a different hormone: amylin, which is co-secreted, alongside insulin, by the pancreas to slow gastric emptying, suppress glucagon secretion and signal feelings of fullness