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390 The ALL-HEART trial, which included patients over the age of 60 with ischemic heart disease but without a history of gout, found that allopurinol did not reduce the incidence of non-fatal myocardial infarction, non-fatal stroke, or cardiovascular death over an average follow-up period of 4.8 years when compared to standard care

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doi: 10.1016/j.immuni.2024.03.002 59 MacDougallA.VolynkinV.SaidiR.PoggioliD.ZellnerH.Hatton-EllisE.et al