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Urban airborne PM(2.5) induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages

Although the vast reserves of stored fat can provide a lot of energy for liver regeneration, excessive lipid accumulation and lipid peroxidation can induce apoptosis of liver cells and cause aseptic inflammation, affecting liver function [10]

Frequent monitoring during and after acute illnesses ensures the medication can be reintroduced safely without further straining kidney function

However, the latest study provides a novel idea for the mechanism of TMAO promoting thrombosis, i.e., an increase in TMAO results in promotion of tissue factor (TF) expression in the vascular endothelium

Given the significant roles of NADPH in numerous pathways of reductive biosynthesis and in the maintenance of cellular redox status, in both the cytosol and the mitochondria, it is not surprising that there are multiple cytoplasmic and mitochondrial enzymes that have, as a product of their reactions, the reduced electron carrier, NADPH