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It is approved to improve glycemic control and reduce cardiovascular risk in adults with type 2 diabetes, often added when lifestyle measures and first-line oral medications are not enough

These effects lead to fewer calories being consumed and, over time, significant weight loss

However, the additional GIP pathway means that stopping tirzepatide involves a more complex physiological adjustment than stopping semaglutide

If you notice diminished response during your next cycle, extend the break to 8 weeks

Less hungry With reduced hunger, many people may skip meals or eat far less than their body needs, risking inadequate intake of essential nutrients, including protein, vitamins, and minerals