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SOD1 and SOD3 contain copper and zinc, whereas SOD2, the mitochondrial enzyme, has manganese in its reactive centre

doi:10.5455/msm.2021.33.60-64

Care should be taken to treat venous disease conservatively first as there is no data showing correction of venous insufficiency by surgical means will improve lipedema

Hashimoto thyroiditis is often associated with type 1 diabetes and other autoimmune disorders such as coeliac disease, type 2 and type 3 polyglandular autoimmune disorders (APS)

Autoimmune thyroid disease is associated with both increased rates of miscarriage, for which the appropriate medical response is uncertain at this time, and postpartum thyroiditis