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Piche ME, Tchernof A, Despres JP, Phenotypes O

Semaglutide is a GLP-1 receptor agonist originally developed for type 2 diabetes that has demonstrated significant weight loss benefits in clinical trials, with patients losing an average of 15% of body weight over 68 weeks

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Therefore, this study provided the first evidence of functional GLP-1R expression in human iTreg cells, and suggested that GLP-1R might play a key role in the anti-inflammatory effects attributed to GLP-1RA