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Participants were studied at Baylor College of Medicine and underwent: (a) baseline studies of glucose tolerance test, physical function tests (gait speed, upper and lower extremity strength, and rapid 6-minute walk test to assess exercise capacity), DEXA and liver scans, calorimetry, tracer studies (palmitate and acetate), and muscle biopsy

17 It has become clear from studies with the purified enzyme that eNOS may become uncoupled in the absence of the NOS substrate L-arginine or the cofactor BH 4

Following Laviss work, we found that introducing an azetidine group to RT can boost its quantum yield to 2.9%, which is threefolds of that of ThiolQuant Green

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ISBN 978-1-4987-5429-3