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PMID: 21263087

Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP cleavage

ETA simultaneously inhibits both COX and LOX inflammatory pathways, which is why GLM has clinical effects fish oil alone may not match

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