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So, its hard to take anything from that other than: thats interesting, we should do a better study. The overwhelming majority of research comes from rodent models, not humans

Due to the overlapping inhibitory profile of CD and Cyto D [65], caveolae, clathrin mediated or macropinocytotic pathways may participate in the 3-PLG uptake in brain endothelial cells

doi: 10.1016/j.ejphar.2019.02.031 154 SeymourMPtavyFChiesaFPerryHLukeyPTBinksMet al

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This genetically determined variation in 1-C cycle activity associated with increased stress sensitivity may contribute to alterations in neurocognitive functioning and mood regulation