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Healthcare providers typically prescribe semaglutide for patients who need help managing their blood sugar and weight

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Clinical trial data and post-marketing surveillance have not confirmed an increased incidence of medullary thyroid carcinoma in GLP-1RA-treated patients, though long-term monitoring continues [30,31]

The limited impact of AKT inhibition on GSK3 phosphorylation suggested that this interaction is unlikely to represent the dominant mechanism by which Ssu72 regulates GSK3 activity