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Its a medication in the glucagon-like peptide-1 receptor agonist (GLP-1) group of drugs, similar to Wegovy (semaglutide) and Zepbound (tirzepatide), which are also used for weight management

The compound was developed to engage with the melanocortin receptors impacting melanin synthesis

Comment on The risk of going small: lowering GRWR and overcoming small-for-size syndrome in adult living donor liver transplantation

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Menaker described PDE as a "piece of sensationalist fiction and tabloid journalism masquerading as a documentary" and an "exercise in media sensationalism"