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The glucagon like peptide 1 analogue, exendin-4, attenuates oxidative stress-induced retinal cell death in early diabetic rats through promoting Sirt1 and Sirt3 expression
While GLP-1 focuses heavily on satiety, GIP is thought to act more directly on how the brain processes energy and fat storage
It controls food intake and energy expenditure of the body, even if the exact mechanism of satiety regulation is not fully understood
Moreover, weight loss induced by retatrutide has been associated with improvements in insulin sensitivity, lipid profile, and blood pressure
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