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Serum methylmalonic acid (MMA) can also be used as a functional test of vitamin B12 activity

A sublingual or spray MAY help but it will not be enough alone and doesnt work for everyone

Signs of cobalamin deficiency in dogs A dog with cobalamin deficiency may have one or more of the following symptoms: Lethargy Loss of appetite Change in eating habits Dull coat Loss of muscle mass Weight loss Weakness Diarrhea Loss of interest in playing Failure to thrive Mental dullness Seizures Cobalamin deficiency in dogs primarily occurs when there is a problem with cobalamin absorption

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It also modulates serotonin and dopamine