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Rather than single-protocol dosing, PlexusDx integrates optional Precision Peptide Genetic Testing to help contextualize individual variation in GLP-1-pathway genes

Rival Eli Lillys tirzepatide, the active ingredient in Mounjaro and Zepbound, showed in a mid-stage trial that up to 74 percent of patients achieved absence of MASH with no worsening of fibrosis

Our study extends beyond the work of Xie and colleagues by examining an even broader range of clinical outcomes (up to 1,026 phenotypes) while leveraging electronic health record (EHR) data from the All of Us Research program (AOU), 65 a nationally recruited EHR-linked biobank specifically designed to oversample groups historically underrepresented in biomedical research

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Conclusion Initiation of GLP-1 RAs in a real-world setting is associated with a reduced risk of albuminuria progression and possible mitigation of kidney function loss in patients with T2D and mostly preserved kidney function